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Genetic association of miRNAa with systemic lupus erythematosus in Europeans through decreased expression of the gene. Analysis was adjusted for the first three principal components calculated from AIMs, and gender. Our aim was therefore to examine, localize and validate CD SLE association in a large multi-ethnic population. A high-density admixture map for disease gene discovery in African Americans. Kimberly13 Graciela S.





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Madalena Martins1, 2 Adrienne H. Supplementary Information accompanies this paper on Genes and Immunity website http: This mechanism could be responsible for the shared association of several autoimmune diseases with CD In our study, the 11 significant SNPs were also all located in intron 1 although in different variants; as indicated by the green dots in Figure 1. The top plot shows the negative logarithms of the P- values for genotypic association under the additive model and adjusted for the first three principal components and gender for the polymorphisms successfully genotyped by us in the Asian population green dotsand the significant SNPs from GWAS data 19 dark blue dots; personal communication from authors, May

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Supplementary Information accompanies this paper on Genes and Immunity website http: Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap. The publisher's final edited version of this article is available at Genes Immun. Madalena Martins1, 2 Adrienne H. Langefeld3 and Constantin Fesel 2. National Center for Biotechnology InformationU.